The Xenobe Research Institute (XRI) was founded in 2004 with the goal of advancing natural products towards the clinic. Its specific aim is simple, to help raise awareness and interest in natural product research. XRI is a small non-profit research institute run by one individual, Dr. James La Clair. Its efforts have led to a modest series of publications and federally funded grants. To quell any potential rumors that may exist, Dr. La Clair does not take salary from this program nor does he use this program to lure in collaborators to take advantage of them. The Institute was launched as a tool to help the community in all honesty. To date, XRI has gained a reputation for its high level of generosity often routing the lion-share of its federal funding through its collaborators laboratories.